Iranian Journal of Neurosurgery

en Tuberous Sclerosis: An Overview of All Aspects of the Disease Based On a Pediatric Case Brain Tumors Case report <div style="text-align: justify;">Background and Importance:Tuberous sclerosis, also known as Bourneville's disease is a rare autosomal dominant disease affecting multiple systems. In this case report, we emphasize the importance of clinical criteria instead of genetic analysis in diagnosing tuberous sclerosis and the need for rigorous follow-up of patientsto prevent complications. Case Presentation: Here we present a case of a 10-year-old boy presenting with intractable seizure and hypo-pigmented patches on his face and back of trunk. In neuroimaging evaluation, subependymal giant cell astrocytoma was diagnosed. Further, hisabdominal ultrasound showed multiple hamartomatous lesions in the liver and bilateral kidney. His cardiology and dental evaluation were normal. The dermatologist diagnosed a shagreen patch on the back of his trunk. Based on the latest clinical diagnostic criteria, he was diagnosed with a case of tuberous sclerosis and has been on the rigorous follow-up ever since. Conclusion: Since tuberous sclerosis is a multisystem disease, early diagnosis is necessary to prevent acute symptoms and prevent long-term complications. Here we emphasize the need to use clinical criteria instead of genetic study for early diagnosis of tuberous sclerosis.  </div> Tuberous sclerosis, Hamartomas, Shagreen patch, Angiomyolipoma 0 0 http://irjns.org/browse.php?a_code=A-10-424-3&slc_lang=en&sid=1 Tamajyoti Ghosh tamajyoti@gmail.com 10031947532846009310 10031947532846009310 Yes Senior Resident of Neurosurgery, Department of Neurosurgery,NEIGRIHMS, Shillong, India Binoy Binoy K Singh drbinoysingh@yahoo.com 10031947532846009311 10031947532846009311 No Associate Professor of Neurosurgery, Department of Neurosurgery,All India Institute of Medical Sciences, Raipur, India