en Spine Case report <div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:11pt"><span style="line-height:180%"><b><span lang="EN">Background and Importance:</span></b><span lang="EN"> Ossification of the ligamentum flavum (OLF) is a pathological condition that affects the yellow ligaments, mostly in adult males between the ages of 45 to 70. Ossification is more common in the thoracolumbar region with an accompanying progressive neurological deficit, and its occurrence within the cervical spine is quite rare. Ossification of the yellow ligament is so common in East Asian countries that </span><span lang="EN"><span style="color:black">it is regarded as a frequently occurring aging pathology in the people of this region. </span>Its existence in other ethnic groups is significantly lower.</span></span></span><br> <span style="font-size:11pt"><span style="line-height:180%"><b><span lang="EN">Case Presentation:</span></b><span lang="EN"> A 68-year-old Iranian woman with progressive quadriparesis is presented. Cervical computerized tomography and MRI scans revealed two-level, bilateral, posteriorly located, ossified masses occurring at the C4-C5 and C5-C6 levels, which coincided with the ossification of the yellow ligament. Cervical laminectomy and excision of both masses were undertaken and the patient gradually recovered from his resultant neurological symptoms.</span></span></span><br> <span style="font-size:11pt"><span style="line-height:180%"><b><span lang="EN">Conclusion:</span></b><span lang="EN"> Symptomatic cervical OLF is a markedly rare pathological finding and is typically illustrated as a medical case report. In a careful review of the literature including the presented patient, we could uncover only 77 cases involving a documented symptomatic cervical OLF.</span></span></span></span></div> Cervical myelopathy, Spine, Calcification of ligamentum flavum, Ossification of ligamentum flavum, Ossification of the posterior longitudinal ligament 127 132 http://irjns.org/browse.php?a_code=A-10-126-4&slc_lang=en&sid=1 Abolfazl Rahimizadeh a_rahimizadeh@hotmail.com 100319475328460011303 100319475328460011303 Yes Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, University of Medical Sciences, Tehran, Iran Seyed-Ali Ahmadi 100319475328460011304 100319475328460011304 No Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, University of Medical Sciences, Tehran, Iran Housain Soufiani 100319475328460011305 0009-0000-6894-476X No Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, University of Medical Sciences, Tehran, Iran Walter L. Williamson 100319475328460011306 100319475328460011306 No Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, University of Medical Sciences, Tehran, Iran Mahan Amirzadeh 100319475328460011307 100319475328460011307 No Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, University of Medical Sciences, Tehran, Iran Shaghayegh Rahimizadeh 100319475328460011308 100319475328460011308 No Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, University of Medical Sciences, Tehran, Iran