en Brain Tumors Case report <div style="text-align: justify;"><strong>Background and Importance</strong>: Chondrosarcoma is a rare malignant cartilage forming tumor, usually arising from long bones and rarely observed in the cranium. In the cranium, it commonly arises from the skull base with the skull vault being a highly unusual site.&nbsp;<br> <strong>Case Presentation</strong>: We present the case of a 30-year female presenting with complaints of headache for 6 months. The patient was found to have large chondrosarcoma in the right frontoparietal region, which is an extremely rare location. The final diagnosis was based on histological examination, suggestive of well-differentiated chondrosarcoma [the World Health Organization (WHO); grade I].&nbsp;<br> <strong>Conclusion</strong>: Cranial vault chondrosarcoma is an uncommon histological diagnosis with surgery as the primary treatment option; however, adjuvant radiotherapy plays a definitive role, especially in aggressive or incomplete removed cases.&nbsp;</div> Brain neoplasm, Brain tumor 119 124 http://irjns.org/browse.php?a_code=A-10-409-1&slc_lang=en&sid=1 Keshav Mishra dr.keshav666@gmail.com 10031947532846006670 10031947532846006670 No Department of Neurosurgery, SMS Medical College, Rajasthan, India Somnath Sharma soms.sms@gmail.com 10031947532846006671 10031947532846006671 No Department of Neurosurgery, SMS Medical College, Rajasthan, India Devendra K. Purohit devendrapurohit@rediffmail.com 10031947532846006672 10031947532846006672 Yes Department of Pathology, SMS Medical College, Rajasthan, India Arpita Jindal drarpitajindal@gmail.com 10031947532846006673 10031947532846006673 No Department of Pathology, SMS Medical College, Rajasthan, India